Status checked Oct 25, 2026, 12:35 AM · America/New_York
Observed Sep 21, 2026, 8:00 PM UTC · Last available price
The latest observed price above is market data. Forecast starting prices are issuance-frozen values and are labelled separately in Model Forecast below.
Vertex Pharmaceuticals Incorporated (VRTX) stock forecast and scoring
Review the dated model forecast and five-factor Scorecard for VRTX. Each has its own availability and reference date; a score is a relative comparison, not a price prediction.
12M forecast summary
Target date · Sep 21, 2027
Lower Estimate (P10)
$346.68
-32.1%
Median Estimate (P50)
$546.06
+6.9% from starting price
Upper Estimate (P90)
$719.68
+40.9%
$346.68Median $546.06$719.68
Median Estimate
$546.06
Starting price
$510.72
Change from starting price
+6.9%
Target date
Sep 21, 2027
Data through
Sep 21, 2026
The estimate uses its dated starting price. It does not predict returns from today’s quote.
Vertex Pharmaceuticals Incorporated is a leading biotechnology firm primarily focused on the discovery, advancement, and marketing of innovative treatments, particularly for cystic fibrosis (CF). The company offers a range of approved medications for CF patients, including SYMDEKO/SYMKEVI, ORKAMBI, and KALYDECO, which target specific mutations within the cystic fibrosis transmembrane conductance regulator gene. Additionally, they provide TRIKAFTA for individuals with CF aged six years and older who possess at least one F508del mutation. Beyond its established CF therapies, Vertex maintains a robust and diverse clinical pipeline. This includes VX-864, currently in Phase 2 for alpha-1 antitrypsin (AAT) deficiency; VX-147, also in Phase 2, addressing APOL1-mediated focal segmental glomerulosclerosis (FSGS) and other serious kidney conditions; VX-880, a potential treatment for Type 1 Diabetes undergoing Phase 1/2 trials; VX-548, a NaV1.8 inhibitor in Phase 2 for various forms of acute, neuropathic, and musculoskeletal pain; and CTX001, which is in Phase 3 development for severe sickle cell disease (SCD) and transfusion-dependent beta-thalassemia (TDT). The company distributes its pharmaceutical products through specialty pharmacies and distributors across the United States, while international sales are facilitated via a network of specialty distributors, retail chains, hospitals, and clinics. Vertex also engages in numerous strategic collaborations with partners such as Affinia Therapeutics, Arbor Biotechnologies, CRISPR Therapeutics, Kymera Therapeutics, Mammoth Biosciences, Moderna, Obsidian Therapeutics, Skyhawk Therapeutics, Ribometrix, Genomics plc, Merck KGaA, and X-Chem. Established in 1989, Vertex Pharmaceuticals is headquartered in Boston, Massachusetts.
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Research snapshot
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Risk / safety methodology: Safety describes recent price swings and distance from a recent high alongside cash flow and profitability. It is not a credit rating or a promise of protection from loss.
How its valuation measures compare with the group.
Quality
Plus or Pro
How its profitability and operating quality compare.
Safety
71.2
0255075100
Strong
How its price swings, distance from a recent high, cash flow and profitability compare.
Momentum
68.4
0255075100
Strong
How its recent price-trend measures compare.
Company snapshotDescriptive peer comparisonScore date: Sep 22, 2026Historical snapshot
All scores in this Scorecard describe relative characteristics as of the shown date, using historical market data and reported company information; higher scores on the 0–100 scale indicate more favorable characteristics in the relevant comparison group, and none forecasts future performance.
Scores are relative comparisons, not absolute grades: companies with different coverage may be scored on different inputs. Peer positions and input coverage can differ by factor; use the displayed comparison group and date when comparing readings. An 80 is not an 80% chance of a price rise. These scores are not price forecasts or recommendations.
The rank with complete inputs compares only companies with every input for that factor, using the issued scores. Equal partial coverage percentages do not establish matching inputs. Current stockwide snapshots use matching input groups; older snapshots may use a smaller fixed group. Scores do not separately adjust for industry or company size. Growth readings do not establish multi-year persistence or separate share-count effects from EPS growth. Scores are independent of the selected forecast horizon.
Research snapshot
Latest update · 2026-09-21
View Plans to read the previous successful update.
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Start with profit, cash generation and financial flexibility. Scores describe relative characteristics and do not predict returns.
Revenue · trailing 12 months
$12.62B
2025-07-01 to 2026-06-30
Net income · trailing 12 months
$4.41B
2025-07-01 to 2026-06-30
Free cash flow · trailing 12 months
$3.8B
2025-07-01 to 2026-06-30
Consolidated debt
$1.98B
At 2026-06-30
Dates and reporting periods
Market observations, financial reporting periods and report dates can differ. Each measure shows its own period.
Research data through 2026-09-21
Update published 2026-09-22
Currency: USD
Company comparison
Compare company metrics only when their currency, observation date and reporting periods agree. Similar companies are starting points for research, not substitutes for each other.
12-month forecasts show model median estimates (P50), with changes from each forecast’s starting price. Headline scores describe dated company characteristics; they do not predict future performance.